Clinicopathologic features and prognosis of primary squamous cell carcinoma of the thyroid: report of 16 patients

VernacularTitle:16例原发性甲状腺鳞状细胞癌的临床病理特征及预后分析
Author: Wei ZHANG ¹ ; Chuanxiang HU ¹ ; Linfei HU ¹ ; Wenyuan CHENG ¹ ; Xiangqian ZHENG ¹
Author Information

1. 天津医科大学肿瘤医院甲状腺颈部肿瘤科　国家恶性肿瘤临床医学研究中心　天津市恶性肿瘤临床医学研究中心　天津市肿瘤防治重点实验室，天津　300060
Publication Type:Journal Article
Keywords: Thyroid neoplasms; Pathology, clinical; Prognosis
From: Chinese Journal of General Surgery 2024;39(12):909-913
CountryChina
Language:Chinese
Abstract: Objective:To evaluate the clinicopathologic characteristics and prognosis of primary squamous cell carcinoma of the thyroid (PSCCT).Methods:We reported 16 cases who were operated on and histologically diagnosed with primary squamous cell carcinoma of the thyroid from Jan 2012 to Dec 2016.Results:Among the 16 patients with PSCCT,there were 10 females (62%) and 6 males (38%),mean age was (58.13±11.21) years old. Univariate analysis showed that gender ( χ2=4.367, P=0.037), tumor size ( χ2=5.630, P=0.018) and radical surgery ( χ2=11.123, P=0.001) were important predictive factors for overall survival.COX regressing analysis showed radical surgery was independent prognostic factors ( P=0.034). Conclusions:PSCCT is a rare thyroid cancer with an aggressive nature and poor prognosis. Radical surgery was associated with a fair outcome.