Problems to be faced in the treatment of colorectal cancer in patients with Lynch syndrome
10.3760/cma.j.cn113855-20241202-00744
- VernacularTitle:林奇综合征患者结直肠癌治疗需要面对的问题
- Author:
Zhenjun WANG
1
Author Information
1. 首都医科大学附属北京朝阳医院普外科，北京 100020
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Syndrome
- From:
Chinese Journal of General Surgery
2025;40(2):85-87
- CountryChina
- Language:Chinese
-
Abstract:
The success of recent immunotherapy and target immunotherapy further shows the importance of MDT model for colorectal cancer and other related cancers in patients with Lynch syndrome characterized by mismatch repair defect molecular pathology, which urges doctors to first choose targeted drug for suitable patients and develop methods that can accurately judge the curative effect,to study whether we should adopt the "down-scaled version" radical surgery to achieve the goal of radical cure, and to study whether PD-1 inhibitors can prevent the occurrence of Lynch syndrome malignant tumor and achieve organ preservation to a greater extent.
