Correlation between Estimated Pulse Wave Velocity and Retinopathy in Patients with Type 2 Diabetes Mellitus
10.11969/j.issn.1673-548X.2025.06.013
- VernacularTitle:估算脉搏波传导速度与2型糖尿病患者视网膜病变的关联
- Author:
Yao XIAO
1
;
Mingjun XU
;
Shuwu WEI
Author Information
1. 100053 北京,中国中医科学院广安门医院;100029 北京中医药大学
- Publication Type:Journal Article
- Keywords:
Estimated pulse wave velocity;
Arterial stiffness;
Diabetic retinopathy;
Risk factors
- From:
Journal of Medical Research
2025;54(6):70-75
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between estimated pulse wave velocity(ePWV)and diabetic retinopathy(DR).Methods Totals of 7468 patients with type 2 diabetes mellitus(T2DM)who were hospitalized from January 2018 to December 2022 were retrospectively selected and classified into the DR group and the no DR group based on fundus examination.Logistic regression was used to analyze the relationship between ePWV,its quartile and cutoff value strata,and the prevalence of DR.Results The ePWV level in the DR group was significantly higher than that in no DR group(P＜0.001);the prevalence of DR was significantly higher in the remaining three groups compared to the lowest quartile of ePWV(Q1 23.2％,Q2 30.4％,Q3 31.9％,Q4 30.1％,P＜0.001);the ePWV cutoff value was 9.27m/s,and the high ePWV group DR prevalence was significantly higher than in the low ePWV group(30.9％vs 22.4％,P＜0.001).ePWV was a risk factor for DR prevalence(OR=1.070,P＜0.001)but was affected by age,sex,diastolic blood pres-sure,lipids,and renal function;whereas,ePWV＞9.27m/s was a risk factor for the prevalence of DR independently of diabetes-related factors(OR=1.421,P＜0.001)and general condition and other confounding factors(OR=1.494,P＜0.001)in addition to risk fac-tors for DR prevalence.Conclusion ePWV was associated with DR prevalence,and T2DM patients with high ePWV levels were at high-er risk of having DR.
