Caveolin-1 and retinal neovascularization diseases
10.13389/j.cnki.rao.2025.0029
- VernacularTitle:Caveolin-1与视网膜新生血管性疾病
- Author:
Wanyu TANG
1
;
Rui ZHANG
;
Yalong DANG
Author Information
1. 476600 河南省洛阳市,河南科技大学临床医学院,河南科技大学第一附属医院眼科
- Publication Type:Journal Article
- Keywords:
Caveolin-1;
retinal neovascularization;
mechanism of action
- From:
Recent Advances in Ophthalmology
2025;45(2):156-160
- CountryChina
- Language:Chinese
-
Abstract:
Retinal neovascularization is a common pathological feature of many blinding eye diseases,and these neovessels are usually fragile and prone to rupture and hemorrhage,which can lead to severe visual impairment.Caveolin-1 is an important membrane protein involved in cellular signaling,lipid metabolism,and cytoskeleton regulation.Currently,it has been proven that Caveolin-1 expresses in a variety of retinal cell types and can participate in retinal neovascularization by regulating multiple signaling pathways.In this article,the domestic and international studies on the role and mechanism of Caveolin-1 in neovascularization were reviewed,and the therapeutic prospect of Caveolin-1 in retinal neovascularization ophthalmopathy was analyzed.This study aims to provide ideas for exploring the pathogenesis of the disease and seeking potential targeted interventions.
