Progress of research and pathogenesis on the role of cellular senescence in retinal diseases
10.13389/j.cnki.rao.2025.0027
- VernacularTitle:细胞衰老在视网膜疾病发病机制中的作用研究进展
- Author:
Lifang BAI
1
;
Ying WANG
Author Information
1. 410000 湖南省长沙市,中南大学爱尔眼科研究院
- Publication Type:Journal Article
- Keywords:
cellular senescence;
diabetic retinopathy;
age-related macular degeneration
- From:
Recent Advances in Ophthalmology
2025;45(2):145-150
- CountryChina
- Language:Chinese
-
Abstract:
Characterized by cell cycle arrest and irreversible loss of cell proliferation,cellular senescence is a normal physiological phenomenon and also a pathological stress response of cells under abnormal stimulation.The pathogenesis of retinal diseases is complex,and there are few treatment methods with poor effects.Recent studies have shown that cellular senescence is involved in the occurrence and development of some retinal diseases.This paper focuses on the role of cellu-lar senescence in retinal diseases,its influence on the occurrence and development of retinal diseases,and the progress of treatment.