Construction of Prediction Models for Hepatic Sinus Obstruction Syndrome and Budd-Chiari Syndrome
10.11969/j.issn.1673-548X.2025.06.008
- VernacularTitle:肝窦阻塞综合征与布-加综合征预测模型的构建
- Author:
Caili MA
1
;
Dawei YANG
;
Zhenghan YANG
Author Information
1. 100050 首都医科大学附属北京友谊医院放射科;100010 北京市隆福医院放射科
- Publication Type:Journal Article
- Keywords:
Hepatic sinusoidal obstruction syndrome;
Budd-Chiari syndrome;
Risk factor
- From:
Journal of Medical Research
2025;54(6):39-43,81
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a predictive model for hepatic sinusoidal obstruction syndrome(HSOS)and Budd-Chiari syn-drome(BCS),and to evaluate the performance of the model.Methods From April 2016 to February 2024,20 patients with HSOS and 40 patients with BCS who were first discharged from the Beijing Friendship Hospital Affiliated to Capital Medical University hospital infor-mation system(HIS)system were retrospectively collected.The clinical data of all patients were extracted,and the independent risk fac-tors for HSOS were screened by multi-factor Logistic regression method,and the differential diagnosis model was established accordingly,and then the efficacy was evaluated by receiver operating characteristic(ROC)curve.Results Multivariate Logistic regression analysis showed that hepatic vein stenosis or unclear display(OR=39.441,95％CI:5.928-262.429)was an independent risk factor for HSOS,and paravertebral vein opening was an independent protective factor for HSOS(OR=0.026,95％CI:0.002-0.285).Based on the above two parameters,a prediction model for HSOS in patients with hepatic venous outlet tract obstruction was established.The ROC curve showed that the area under the curve(AUC)of the model was 0.922(95％CI:0.864-0.991),with the sensitivity of 85.0％and the specificity of 92.5％.Conclusion Hepatic vein stenosis or unclear display is an independent risk factor for HSOS in patients with hepatic vein outflow tract obstruction during hospitalization,and the model constructed can predict the risk of HSOS.
