The short-term effect of multielement intergration sound on tinnitus and its influence on HbO con-centration in frontal polar cortex
10.3969/j.issn.1006-7299.2025.04.010
- VernacularTitle:多元复合声治疗耳鸣的短期疗效及其对额极皮层氧合血红蛋白浓度的影响
- Author:
Qingchun PAN
1
;
Bei LI
;
Xueqin MI
;
Xiaoying SONG
;
Xiaoming TANG
;
Yuanling WANG
;
Jing ZHANG
Author Information
1. 川北医学院附属医院耳鼻咽喉头颈外科(南充 637000)
- Publication Type:Journal Article
- Keywords:
Tinnitus;
Multielement integration sound;
Frontal pole;
Oxyhemoglobin
- From:
Journal of Audiology and Speech Pathology
2025;33(4):348-352
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify the hemodynamic characteristics of frontal polar cortex(FPC)in patients with chronic subjective tinnitus,and to study the short-term efficacy of multielement integration sound(MIS)treatment,and its effects on FPC oxyhemoglobin(HbO).Methods Fifty patients with chronic subjective tinnitus(tinnitus group)and 50 subjects without tinnitus matching their age,sex and education level(control group)were collected from June 2023 to Oc-tober 2023.The tinnitus group and control group received MIS treatment for 15 minutes,respectively.Tinnitus handicap inventory(THI)and visual analogue scale(VAS)scores were collected before and after treatment in tinnitus group.Func-tional near infrared spectroscopy(fNIRS)was used to measure the 8-minute average HbO concentration in the frontal cortex of both groups before and after treatment.The changes of HbO concentration before and after treatment were compared be-tween the two groups.The correlation between clinical features and HbO was analyzed.Results The VAS score of the tin-nitus group decreased after short-term MIS treatment.The HbO concentration of FPC in tinnitus group was higher than that in control group before treatment.The HbO concentration of FPC in tinnitus group was decreased by MIS short-term treatment.The difference of HbO concentration before and after treatment(ΔHbO)was positively correlated with the difference of VAS score before and after treatment(ΔVAS)in the tinnitus group.Conclusion The hemodynamics of the frontal polar cortex in chronic subjective tinnitus patients is different from that of in non-tinnitus control group.MIS can change the hemodynamics of the frontal polar cortex in chronic subjective tinnitus patients.The frontal polar cortex may be the site of MIS.
