A case report of ischemic bowel disease caused by Shengxuexiaoban capsules
10.12173/j.issn.1005-0698.202408096
- VernacularTitle:升血小板胶囊致缺血性肠病1例分析
- Author:
Cuilin XU
1
;
Binbin LI
;
Jing HU
;
Naizhong HU
;
Yanyan WANG
Author Information
1. 亳州市中医院药学部(安徽亳州 236800);安徽医科大学第一附属医院药剂科(合肥 230000)
- Publication Type:Journal Article
- Keywords:
Shengxuexiaoban capsules;
Ischemic bowel disease;
Adverse reactions
- From:
Chinese Journal of Pharmacoepidemiology
2025;34(2):236-240
- CountryChina
- Language:Chinese
-
Abstract:
A 76-year-old male patient with lung cancer developed thrombocytopenia due to chemotherapy.Three days after taking the Shengxuexiaoban capsules orally,he experienced abdominal pain and bloody stool and was admitted to the hospital.The blood test showed white blood cell count of 11.54×109·L-1,neutrophil percentage of 82.4％,platelet count of 93×109·L-1,and C-reactive protein level of 23.50 mg·L-1.Fecal occult blood test positive,and pathology indicatesd ischemic-like changes in the rectal mucosa.The patient was diagnosed with ischemic bowel disease.After treatment with fluid replacement and anti-infection,the patient's abdominal pain disappeared and his stool turned yellow.The Naranjo's Assessment Scale was used to evaluate the association between adverse effects of ischemic bowel disease and Shengxuexiaoban capsules,and the result was very likely related.This article analysed the clinical characteristics and drug treatment process of ischemic bowel disease caused by Shengxuexiaoban capsule through this case,aiming to provide references for the safe use of drugs in the clinically.
