Current status analysis of anti-infection research by using the Bayesian method
10.12173/j.issn.1005-0698.202408053
- VernacularTitle:应用贝叶斯方法的抗感染领域研究现况分析
- Author:
Yiling LIU
1
;
Jinglin LIU
;
Zhenzhen LU
;
Yingying WANG
;
Qijing JIANG
;
Bingzhe LI
;
Luyan DAI
;
Fanrong YAN
;
Lihong HUANG
Author Information
1. 复旦大学附属中山医院生物统计室(上海 200032);中国药科大学理学院(南京 211198)
- Publication Type:Journal Article
- Keywords:
Bayesian method;
Anti-infection research;
Research features
- From:
Chinese Journal of Pharmacoepidemiology
2025;34(1):69-77
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the application characteristics,trends,and special advantages of anti-infection research using the Bayesian method,and to provide methodological reference for the development of anti-infection research.Methods PubMed,CNKI and WanFang Data were electronically searched for the studies on anti-infection using Bayesian method published from January 1,2015 to November 21,2023.The relevant information of publication time,anti-infection type,sample size,Bayesian characteristics and Bayesian application pattern were analyzed descriptively and reviewed.Results A total of 86 studies were included,of which 41.9％were observational studies,only 7.0％were enterprise-initiated studies,and 48.8％were mentioning prior information studies.There was no domestic intervention study.The application characteristics and advantages of Bayesian method in intervention study,observational study and pharmacokinetic study are different.In intervention researches and observational researches,the application of Bayesian design decision and the application of Bayesian analysis and estimation accounts for 69.2％and 52.8％at most,respectively.Conclusions The Bayesian method is flexible,can be used for small sample sizes and complex model research,and can deal with uncertainty.In intervention studies in the field of anti-infection in China,the Bayesian method has not been applied widely.Only a handful of studies applying Bayesian method have been initiated by companies.In the future,it is still necessary to promote the advantages and application scenarios of Bayesian methods in the field of anti-infection research and strengthen the standardization of the application of Bayesian method.
