Research progress of placenta-derived exosomes in gestational diabetes mellitus
10.3969/j.issn.1006-6187.2025.07.014
- VernacularTitle:妊娠期糖尿病胎盘来源外泌体的研究进展
- Author:
Shuhui YIN
1
;
Jie YANG
Author Information
1. 010013 呼和浩特,内蒙古自治区国际蒙医医院临床检验中心
- Publication Type:Journal Article
- Keywords:
Exosomes;
Extracellular vesicles;
Gestational diabetes mellitus;
RNA;
Placenta
- From:
Chinese Journal of Diabetes
2025;33(7):554-556
- CountryChina
- Language:Chinese
-
Abstract:
Pregnancy is a complex biological process of human body,involving the growth and development of the embryo and the formation of the placenta and other stages.Placental-derived exosome(PdE)is secreted by various placental cells and is rich in various RNA,DNA,protein and lipids.PdE,as active carriers of molecular biomarkers and mediators of cell-to-cell communication,regulate the physiological functions of the mother and maintain the normal development of the fetus,and participate in the pathological process of pregnancy.This review examines the roles of placental microRNAs,long-chain non-coding RNAs,circular RNAs in gestational diabetes mellitus,focusing on their molecular mechanisms and potential as biomarkers for early diagnosis and therapeutic targets.
