An analysis of factors related to cervical lymph node metastasis in papillary thyroid microcarcinoma
10.3760/cma.j.cn113855-20240529-00391
- VernacularTitle:多灶性甲状腺微小乳头状癌颈部淋巴结转移相关因素分析
- Author:
Wenchao AN
1
;
Wenbin YU
Author Information
1. 内蒙古医科大学研究生院，呼和浩特 010000
- Publication Type:Journal Article
- Keywords:
Thyroid carcinma, papillary;
Lymphatic metastasis;
Risk factors
- From:
Chinese Journal of General Surgery
2024;39(12):924-928
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the related risk factors and clinical application value of lymph node metastasis in the pre laryngeal, pre tracheal, and para tracheal regions of multifocal papillary thyroid microcarcinoma.Method:The clincal data and of 629 patients with papillary thyroid microcarcinoma admitted to Peking University Cancer Hospital-Inner Mongolia Hospital from Feb 2023 to Apr 2024 were collected, for the incidence of lymph node metastasis in the central region of the neck, and the relationship between relevant factors and the central lymph node subregions.Result:Univariate analysis showed that gender, age, tumor diameter, and whether or not combining Hashimoto's thyroiditis were associated with paratracheal lymph node metastasis; Capsular invasion was associated with pre-tracheal and paratracheal lymph node metastasis, and gender, number was correlated with pre-laryngeal lymph node metastasis (all P<0.05). The results of multivariate analysis showed that male, age <55 years, and capsular invasion were independent risk factors for paratracheal lymph node metastasis ( χ2=8.331, P=0.004; χ2=9.139, P=0.003;χ 2=4.798, P=0.028); Male and multiple lesions (≥2 lesions) are independent risk factors for lymph node metastasis in the larynx ( χ2=7.182, P=0.007; χ2=5.541, P=0.019). Conclusions:Central lymph node metastasis in patients with papillary thyroid microcarcinoma is closely related to factors such as gender, age, tumor diameter, and capsular invasion, with the highest metastasis rate observed in the paratracheal lymph nodes.
