Research progress on the regulatory role of placental function in maternal motion-mediated fetal metabolic programming
10.3969/j.issn.1006-6187.2025.07.012
- VernacularTitle:母体运动介导胎儿代谢编程中的胎盘功能调控作用的研究进展
- Author:
Shixuan ZHANG
1
;
Ling ZHANG
1
;
Junqing ZHANG
1
;
Jia ZHENG
1
Author Information
1. 100034 北京大学第一医院内分泌科
- Publication Type:Journal Article
- Keywords:
Maternal exercise;
Fetal metabolic programming;
Glucose and lipid metabolism;
Placenta;
Epigenetic modifications
- From:
Chinese Journal of Diabetes
2025;33(7):546-549
- CountryChina
- Language:Chinese
-
Abstract:
The theory of fetal metabolic programming indicates that an adverse developmental environment during the mother's pregnancy can significantly increase the risk of chronic metabolic diseases such as obesity,diabetes mellitus and cardiovascular diseases in the offspring in adulthood.Exercise during pregnancy can effectively improve and even reverse the disorders of glycolipid metabolism in offspring caused by poor nutritional environment during pregnancy.The placenta serves as a crucial interface facilitating the exchange of substances and signal molecules between mother and baby,and also plays an important role in mediating fetal metabolic programming and early life intervention.This article reviews the regulatory role of placental function in maternal motion-mediated fetal metabolic programming.
