Recent advance in application of nanomedicine and nano delivery system in neuroinflammation after traumatic brain injury
10.3760/cma.j.cn115354-20250415-00218
- VernacularTitle:纳米药物递送系统在创伤性颅脑损伤后神经炎症中的应用研究进展
- Author:
Hailong LI
1
;
Lili GUO
;
Fan FEI
;
Dong XIANG
Author Information
1. 四川现代医院神经外科,成都 610045
- Publication Type:Journal Article
- Keywords:
Traumatic brain injury;
Neuroinflammation;
Nanomedicine and nano delivery system;
Blood-brain barrier;
Targeted therapy;
Molecular mechanism
- From:
Chinese Journal of Neuromedicine
2025;24(9):945-951
- CountryChina
- Language:Chinese
-
Abstract:
Neuroinflammation secondary to traumatic brain injury (TBI) is a key factor affecting the prognosis and neural repair of patients. In recent years, nanomedicine and nano delivery system (NDDS) has shown great potential in neuroinflammation after TBI due to their controlled release, good biocompatibility, and ability to cross the blood-brain barrier. This article reviews the recent advance in mechanism of neuroinflammation after TBI and regulatory role of various NDDS in neuroinflammation after TBI, with the aim of providing references for treatment of neuroinflammation after TBI.