Clinical analysis of 6 patients with persistent proatlantal intersegmental artery
10.3760/cma.j.cn115354-20250729-00439
- VernacularTitle:永存寰前节间动脉6例临床分析
- Author:
Panxing LI
1
;
Tao QUAN
1
;
Zhiqiang YAO
1
;
Haowen XU
1
;
Sheng GUAN
1
Author Information
1. 郑州大学第一附属医院神经介入科，郑州 450052
- Publication Type:Journal Article
- Keywords:
Persistent proatlantal intersegmental artery;
Vascular malformation;
Intracranial aneurysm;
Acute basilar artery tip occlusion;
Internal carotid artery st
- From:
Chinese Journal of Neuromedicine
2025;24(9):928-932
- CountryChina
- Language:Chinese
-
Abstract:
Objective:Persistent proatlantal intersegmental artery (PPIA) is a rare variant of persistent carotid-vertebrobasilar anastomoses and mostly discovered incidentally. To explore the clinical features of PPIA, and enhance the understanding of this rare cerebrovascular variation.Methods:A retrospective analysis was performed. The clinical data of 6 patients with PPIA admitted to Department of Neurointervention, First Affiliated Hospital of Zhengzhou University from June 2018 to June 2024 were analyzed. The imaging features, associated cerebrovascular diseases, treatments and follow-up results were summarized.Results:Among the 6 PPIA patients, 4 were with type I and 2 were with type II; 5 were with left PPIA and 1 patient was with right PPIA; 5 patients had bilateral vertebral artery hypoplasia or absence, and 1 patient had absence of the ipsilateral vertebral artery and normal development of the contralateral vertebral artery. Four PPIA patients were combined with intracranial aneurysms: 2 patients received dual stent-assisted embolization and flow diverter device combined with covered stent implantation, respectively (after 6 months of follow-up, modified Rankin scale score of 0 indicating good prognosis and healed intracranial aneurysms), and the other 2 patients with micro-aneurysms were not treated. One patient was combined with internal carotid artery stenosis and accepted stent placement (good prognosis at 6 months after follow-up). One patient was combined with acute basilar artery tip occlusion and accepted aspiration thrombectomy (died of brain herniation 7 days after thrombectomy).Conclusions:PPIA is often accompanied by vertebral artery developmental abnormalities and prone to have concurrent intracranial aneurysms or ischemic stroke. When performing surgical treatment for cerebrovascular diseases associated with PPIA, PPIA protection to ensure blood supply of the posterior circulation is essential.
