Research progress on infective endocarditis caused by HACEK group bacteria
10.12138/j.issn.1671-9638.20256615
- VernacularTitle:HACEK组细菌感染性心内膜炎的研究进展
- Author:
Linping WU
1
;
Lin WANG
;
Liyuan CHEN
;
Liqiao SONG
;
Xuexia MA
;
Yuan-ming WANG
;
Shaochen SU
Author Information
1. 兰州大学口腔医学院,甘肃兰州 730000
- Publication Type:Journal Article
- Keywords:
HACEK group microorganisms;
infective endocarditis;
diagnosis and treatment
- From:
Chinese Journal of Infection Control
2025;24(2):267-272
- CountryChina
- Language:Chinese
-
Abstract:
The HACEK group microorganisms(Haemophilus parainfluenzae,Aggregatibacter actinomycetem-comitans,Cardiobacterium spp.,Eikenella corrodens,Kingella kingae)belong to Gram-negative bacilli and are members of the normal oropharyngeal microbiota,which can cause invasive opportunistic infection when the host immune barrier is damaged,with infective endocarditis being one of the most serious diseases.HACEK endocarditis is characterized by an insidious course,prolonged delay of diagnosis,and dependence on third-generation cephalo-sporins for treatment.In recent years,with the emergence and development of 16S ribosomal RNA gene sequencing technique,the rapid diagnosis of this disease is expected to be achieved.This paper summarizes the main clinical characteristics and research progress of infective endocarditis caused by HACEK group bacteria,aiming to provide reference for clinical diagnosis and treatment.
