Recent advance in treatment of Parkinson's disease with traditional Chinese medicine polysaccharides
10.3760/cma.j.cn115354-20241226-00810
- VernacularTitle:中药多糖治疗帕金森病的研究进展
- Author:
Xinyuan HAN
1
;
Yixiao LIU
;
Yitong XIAO
;
Chenxi SUN
;
Tianyuan YE
Author Information
1. 山东中医药大学中医学院，济南 250355
- Publication Type:Journal Article
- Keywords:
Polysaccharide;
Parkinson's disease;
Mechanism
- From:
Chinese Journal of Neuromedicine
2025;24(5):524-531
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson's disease (PD), a major neurodegenerative disease faced by an aging society worldwide, has not yet been fully elucidated in terms of its pathogenesis. Currently, clinical treatment mainly relies on symptom management and can only be relieved by medication. In recent years, many studies have shown that polysaccharides have potential in treatment of neurodegenerative diseases. Polysaccharides play a role in PD in ways such as anti-oxidative stress response, improvement of mitochondrial dysfunction, inhibition of neuroinflammation, anti-neurotoxicity, and activation of autophagy. This study discusses the mechanism of polysaccharides in PD, aiming to provide new ideas for PD prevention and treatment and new drug development in the future.
