Application Value of M-ROSE Combined with Bronchoscopy in Severe Pneumonia
10.11969/j.issn.1673-548X.2025.06.024
- VernacularTitle:微生物学快速现场评价联合支气管镜在重症肺炎中的应用价值
- Author:
Dan XU
1
;
Qian LUO
;
Xiaoli LIU
Author Information
1. 832000 石河子大学医学院;830000 乌鲁木齐,新疆生产建设兵团医院呼吸与危重症医学科
- Publication Type:Journal Article
- Keywords:
Severe pneumonia;
Microbiological rapid onsite evaluation;
Bronchoscopy
- From:
Journal of Medical Research
2025;54(6):133-137,174
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of microbiological rapid on-site evaluation(M-ROSE)combined with bronchoscopy in severe pneumonia.Methods A total of 170 patients with severe pneumonia who met the criteria were enrolled,and they were divided into two groups according to whether M-ROSE was performed or not,with 85 cases in each group.In the M-ROSE group,bronchoscopy was used for alveolar lavage to obtain samples,and then the M-ROSE technology was used to guide the treatment,and the control group was given empiric treatment after bronchoscopic alveolar lavage.The clinical efficacy,antibiotic use,and hospital stay were compared be-tween the two groups.The consistency of M-ROSE and bronchoalveolar lavage fluid(BALF)smears and culture results were compared,and M-ROSE and BALF smears and culture time were compared.Results The total effective rate in the M-ROSE group was higher than that in the control group(P＜0.05).The duration of antibiotic use,cost and hospital stay in the M-ROSE group were lower than those in the control group(P＜0.05).The results of M-ROSE were in better agreement with the results of BALF smear(Kappa=0.799,P＜0.001),and the results of M-ROSE were in good agreement with the results of BALF culture(Kappa=0.609,P＜0.001).Conclusion M-ROSE combined with bronchoscopy is of high value for the initial assessment of pathogens in patients with se-vere pneumonia,and can improve the effective rate of treatment,reduce the time and cost of antibiotic use,and reduce the length of hos-pital stay to a certain extent.
