Correlation between Triglyceride-Glucose Index and Colorectal Polyps
10.11969/j.issn.1673-548X.2025.06.028
- VernacularTitle:甘油三酯葡萄糖指数与结直肠息肉的相关性研究
- Author:
Mengran YAO
1
;
Aihua FEI
1
Author Information
1. 200092 上海交通大学医学院附属新华医院全科医学科
- Publication Type:Journal Article
- Keywords:
Colorectal polyps;
TyG index;
Pathological types;
Screening
- From:
Journal of Medical Research
2025;54(6):155-158,167
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research the correlation between triglyceride-glucose index(TyG)and the risk of colorectal polyps with different pathological types.Methods According to inclusion and exclusion criteria,453 patients who underwent fiberoptic colonoscopy at Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine from May 2022 to December 2023 were selected.Based on colonoscopy results,patients were divided into non-colorectal polyp group and a colorectal polyp group.The polyp group was further classified according to pathological results into non-adenomatous polyps,adenomatous polyps,and colorectal cancer groups.A retrospec-tive analysis was conducted on the general data of the study subjects,including relevant test indicators such as blood glucose and lipids.Logistic regression analysis was employed to identify risk factors associated with the occurrence of colorectal polyps.Receiver operating characteristic(ROC)curves were constructed to evaluate the predictive role of the TyG index in the development of colorectal polyps,and the TyG levels among different pathological types of colorectal polyps were compared.Results Patients in the polyp group exhibited high-er age,male proportion,body mass index(BMI),glycosylated hemoglobin(HbA1c),triglycerides(TG),lipoprotein(a),and TyG in-dex compared to the non-polyp group.After adjusting for confounding factors,Logistic regression analysis indicated a correlation between the TyG index and the occurrence of colorectal polyps(P＜0.05).The area under the curve(AUC)for the TyG index predicting the development of colorectal polyps was 0.756(95％CI:0.702-0.809,P＜0.001).The TyG index level in the non-colorectal polyp group was lower than that in the non-adenomatous polyp,adenomatous polyp,and colorectal cancer groups,with statistically significant differences(P＜0.05).Pairwise comparisons also showed statistically significant differences(P＜0.05).Conclusion The TyG in-dex may be correlated with the occurrence of colorectal polyps.There are significant differences in the TyG index levels among different pathological types of colorectal polyps.
