The application value of dual-energy CT pulmonary perfusion parameters in the evaluation of pulmonary hypertension
10.3969/j.issn.1002-1671.2025.07.010
- VernacularTitle:双能CT肺灌注参数在评估肺高压中的应用价值
- Author:
Wei SUN
1
;
Wangyan LIU
;
Yi XU
;
Yinsu ZHU
Author Information
1. 南京医科大学第一附属医院放射科,江苏 南京 210029
- Publication Type:Journal Article
- Keywords:
pulmonary hypertension;
computed tomography;
computed tomography pulmonary angiography
- From:
Journal of Practical Radiology
2025;41(7):1124-1128
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application value of dual-energy computed tomography(DECT)pulmonary perfusion parameters in the evaluation of pulmonary hypertension(PH).Methods A retrospective selection was performed on 214 patients with suspec-ted PH who underwent DECT pulmonary perfusion examination,and the patients were divided into PH group(n=97)and non-PH group(n=117)according to the pulmonary artery systolic pressure measured by echocardiography.Inter-group comparison,univari-ate and multivariate logistic regression,and the receiver operating characteristic(ROC)curve were used to analyze the two-phase DECT pulmonary perfusion parameters and traditional CT anatomical parameters of the two groups of patients,so as to obtain the best parameters and models for predicting PH.Results There were statistically significant differences in DECT pulmonary perfusion parameters and traditional CT anatomical parameters between the PH group and the non-PH group(P<0.05).In DECT pulmonary perfusion parameters,the ratio of main pulmonary artery enhancement to whole lung enhancement in the pulmonary arterial phase(MPAenh1/WLenh1),the difference between the whole lung enhancement in the pulmonary venous phase and the whole lung enhancement in the pulmonary arterial phase(WLenh2-WLenh1),and in traditional CT anatomical parameters,the main pulmonary artery diam-eter(MPAD)and the ratio of right ventricular diameter to left ventricular diameter(RVD/LVD)were independent predictors of PH.The DECT pulmonary perfusion parameters model had similar diagnostic efficacy to the traditional CT anatomical parameters model for PH,and the combined model of the two parameters had the best diagnostic efficacy,with an area under the curve(AUC)of 0.955 and sensitivity and specificity of 0.866 and 0.940,respectively.Conclusion DECT pulmonary perfusion parameters can be used to evaluate PH,and the combination of traditional CT anatomical parameters and DECT pulmonary perfusion parameters can significantly improve the diagnostic efficacy of PH.
