Analysis of clinical characteristics of thyroid carcinoma in 57 flying personnel
10.3760/cma.j.cn113854-20230223-00014
- VernacularTitle:57例飞行人员甲状腺癌临床特征分析
- Author:
Zhiyuan MAO
1
;
Yu WANG
1
;
Juqin LIU
1
;
Haiyan YU
1
;
Xiuling XIA
1
;
Lulu SUN
1
;
Hui ZHAO
1
;
Zaiwen FAN
1
Author Information
1. 空军军医大学空军特色医学中心肿瘤科，北京 100142
- Publication Type:Journal Article
- Keywords:
Thyroid carcinoma;
Clinical features;
Flying personnel
- From:
Chinese Journal of Aerospace Medicine
2023;34(2):85-89
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To improve the diagnosis and treatment of thyroid carcinoma in flying personnel by analyzing the clinical characteristics of thyroid carcinoma.Methods:The clinical and pathological data of flying personnel with thyroid carcinoma diagnosed and treated by Air Force Medical Center of PLA from January of 2010 to December of 2022 were retrospectively analyzed. Clinical characteristics such as age, flying hours, aircraft types, thyroid function at diagnosis, and pathological characteristics such as tumor site, tumor size, lymph node metastasis, calcification and sand and Ki-67 positive ratio were collected, and the clinical and pathological characteristics were statistically analyzed.Results:Thyroid nodule was found as the first diagnosis of thyroid carcinoma in 57 flying personnel. The age of onset was 22-58 years old, the median age was 37 years old, the flying hours was 4-18 000 h, and the median flying hours was 2 000 h. Thyroid carcinoma was detected in both thyroid glands, and the histological type was papillary thyroid carcinoma. Thyroid function was normal in most cases when thyroid carcinoma was detected. Lymph node metastasis of thyroid carcinoma was low positively correlated with tumor size ( r=0.304, P=0.021), and was low positively correlated with the positive proportion of Ki-67 ( r=0.360, P=0.006). Other clinical and pathological characteristics did not show clear correlation. With the extension of flying hours, the incidence of lymph node metastasis of thyroid carcinoma increased, and the difference was statistically significant ( χ2=6.32, P=0.012). There was no statistical difference among the clinical characteristics of flying personnel with different age and aircraft types ( P>0.05). Conclusions:The thyroid carcinoma is usually diagnosed without clinical symptoms and the thyroid function is basically normal. The thyroid ultrasound examination should be emphasized during physical examination, and further examination should be conducted for the flying personnel with thyroid nodules.
