Research and prospects of radiation biological effects and protection in deep space exploration missions
10.3760/cma.j.cn113854-20231130-00123
- VernacularTitle:深空探测任务辐射生物效应及防护的研究与展望
- Author:
Yali ZHAO
1
;
Pengbo LOU
1
;
Ming LEI
1
;
Honghui WANG
1
;
Pengfei ZOU
1
;
Hua ZHANG
1
;
Bin WU
1
Author Information
1. 中国航天员科研训练中心航天医学全国重点实验室，北京 100094
- Publication Type:Journal Article
- Keywords:
Cosmic radiation;
Radiation injuries;
Radiation protection;
Biological effects;
Review
- From:
Chinese Journal of Aerospace Medicine
2024;35(1):73-78
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To provide clues for in-depth research on radiation protection in deep space exploration missions by reviewing the biological effects of space radiation and biological protection technologies. Literature resource and selection Domestic and abroad relevant literatures were searched and reviewed. Literature quotation Thirty-nine papers published in China and abroad were cited. Literature synthesis Space radiation is the most important environmental harmful factor that affects the health and mission completion of astronauts in deep space exploration missions. It can cause multiple organ cancers throughout the body, degenerative diseases of cardiovascular, central nervous systems, and ocular lens, and acute radiation syndrome of the bone marrow, brain, and gastrointestinal tracts. The effect mechanisms include free radical production, oxidative stress, DNA and other biomolecular breaks, inflammation, cell apoptosis, and bystander effects. Biological protection can be carried out according to the characteristics of the mechanism at different stages of the development of space radiation effects. Conclusions:Deep space radiation can cause health risks such as cancer, degeneration, and acute radiation syndrome, which can be mainly protected and alleviated by reducing free radicals, promoting DNA repair, and inhibiting cell apoptosis.
