Research on brain network changes induced by virtual reality upper limb rehabilitation robot in hemiple-gic stroke patients
10.3969/j.issn.1001-1242.2025.07.004
- VernacularTitle:虚拟现实上肢康复机器人对脑卒中偏瘫患者脑网络的影响
- Author:
Qinglei WANG
1
;
Youxin SUI
;
Lan ZHU
Author Information
1. 南京医科大学第一附属医院康复医学中心,江苏省 南京市,210029;南京医科大学康复医学院
- Publication Type:Journal Article
- Keywords:
stroke;
upper limb rehabilitation robot;
virtual reality;
functional near-infrared spectroscopy
- From:
Chinese Journal of Rehabilitation Medicine
2025;40(7):995-1001
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study and analyze the brain networks of hemiplegic stroke patients in a resting state or during virtual reality(VR)upper limb rehabilitation robot training by functional near-infrared spectroscopy(fNIRS).Method:Fourteen hemiplegic stroke patients were included in this study as the test group,while 14 healthy subjects were recruited as the control group.The fNIRS data of the two groups were collected during the rest-ing state or the VR upper limb rehabilitation robot training.The functional connectivity(FC)index of the brain network was calculated.Result:①No significant difference was found between the test group and the control group in FC in the rest-ing state(P>0.05).②The overall FC of the control group did not increase significantly in the VR task com-pared with the resting state(P>0.05).But the FC of the LSMA-RPFC increased significantly(P<0.05).③The overall FC of the test group decreased in the VR task compared with the resting state(P<0.05),of which the LSMA-RPFC decreased(P<0.05).④The overall FC of the test group was lower than that of the control group(P<0.05),in which there was a significant difference in FC between LSMA-RSMA,LSMA-LM1,LS-MA-RM1,LSMA-RS1,and LM1-RS1(P<0.05)when the test group and the control group performed the VR upper limb rehabilitation robot training task.Conclusion:VR upper limb rehabilitation robot training can induce plastic reorganization of the extensive sen-sorimotor network in hemiplegic patients with stroke.And the mechanism of improving upper limb function may be related to the FC changes between bilateral SMA and SMA and other brain regions.
