Progress in role of microRNA in mitochondrial dysfunction of Parkinson disease
10.3969/j.issn.1000-4718.2025.07.021
- VernacularTitle:微小RNA在帕金森病线粒体功能障碍中的研究进展
- Author:
Boxiang YUAN
1
;
Tao CHEN
1
;
Zhixuan WANG
1
;
Ersheng WEN
1
;
Jinhua XUE
1
Author Information
1. 赣南医科大学基础医学院,江西 赣州 341000
- Publication Type:Journal Article
- Keywords:
Parkinson disease;
microRNA;
mitochondrial dysfunction;
neurodegenerative diseases
- From:
Chinese Journal of Pathophysiology
2025;41(7):1428-1434
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson disease(PD)is one of the most prevalent neurodegenerative disorders,typically affecting the elderly.The pathogenesis of PD is intricate and involves multiple factors,with mitochondrial dysfunction recognized as a significant mechanism contributing to its development.MicroRNAs(miRNAs)play a crucial role in the onset and pro-gression of PD.This review focuses on recent research concerning miRNAs associated with PD,particularly their impact on mitochondrial dysfunction.The insights gathered here aim to support the early diagnosis and targeted treatment of PD.
