Role of the nervous system in tumor occurrence and development
10.3760/cma.j.cn115354-20240807-00464
- VernacularTitle:神经系统在肿瘤发生发展中的作用
- Author:
Liangyi DONG
1
;
Xiaobing CHEN
;
Saiqi WANG
;
Mingzhen CHENG
;
Yongjing REN
;
Yuhang WANG
;
Wei HU
Author Information
1. 郑州大学第一附属医院胸外科，郑州 450052
- Publication Type:Journal Article
- Keywords:
Nerve system;
Tumor;
Autonomic nerve;
Perineural invasion;
Immunity;
Schwann cell;
Extracellular vesicle
- From:
Chinese Journal of Neuromedicine
2025;24(3):310-316
- CountryChina
- Language:Chinese
-
Abstract:
The nervous system not only affects the core processes of tumors such as proliferation, metastasis and angiogenesis, but is also closely related to symptoms such as tumor-related pain and cachexia. Meanwhile, tumor cells can invade adjacent tissues through nerve pathways to induce perineural invasion, which promotes tumor development. This article reviews the research progress in role of the nervous system in tumor occurrence and development from perspectives of tumor perineural invasion, neurotrophic factors, autonomic and sensory nerves, and influence of the neuroimmune system in tumors, in order to provide new perspective and method for tumor treatment.
