Association analysis between comorbidity with chronic diseases and depressive symptoms in middle-aged and older population
10.3969/j.issn.1000-6729.2025.08.08
- VernacularTitle:中老年人群慢性病共病与抑郁症状的关联性分析
- Author:
Yu SUN
1
;
Yangziye GUO
;
Sifang NIU
;
Fuqin MU
;
Hongguang CHEN
;
Yan LIU
;
Yueqin HUANG
;
Ning LIU
Author Information
1. 山东第一医科大学(山东省医学科学院)公共卫生与健康管理学院,济南 250117;济宁医学院公共卫生学院,山东济宁 272013
- Publication Type:Journal Article
- Keywords:
comorbidity;
depressive symptom;
middle-aged and elderly people
- From:
Chinese Mental Health Journal
2025;39(8):713-719
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the comorbidity rate of chronic diseases and prevalence of depressive symptoms among the middle-aged and elderly population,and explore the association between comorbidity with-chronic disease and depressive symptoms in middle-aged and older people.Methods:A cross-sectional study was conducted in Shandong Province.A total of 9 535 middle-aged and older people aged 45 years and over were recrui-ted.General information questionnaire,the chronic disease information questionnaire and Patient Health Question-naire were used for face-to-face interview to screen symptoms and collect information.Univariate analysis and mult-ivariate logistic regression analysis were employed to explore the association between comorbidity with chronic dis-ease and depressive symptoms.Results:The prevalence of depressive symptoms among middle-aged and older peo-ple was 8.7％,while among those with comorbid chronic diseases,the prevalence of depressive symptoms was 29.6％.Respectively,demonstrating an increasing trend with the number of chronic diseases(P＜0.001).Multiva-riate analysis revealed that comorbid chronic disease(OR=1.47,95％CI:1.22-1.78)were risk factors of depres-sive symptoms.Conclusion:Middle-aged and older people with multiple chronic conditions are more likely to be di-agnosed with depressive symptoms,and the detection rate of these symptoms increases with the number of comorbid chronic conditions.Therefore,it is recommended to strengthen mental health interventions for those with multiple chronic conditions.
