Relationship between insulin resistance,hyperandrogenism,and mitochondrial oxidative stress in polycystic ovarian syndrome
10.3969/j.issn.1671-7856.2024.11.016
- VernacularTitle:PCOS中胰岛素抵抗、高雄激素血症与线粒体氧化应激的关系探讨
- Author:
Qi ZHAO
1
;
Ping CHEN
;
Liping YANG
;
Jianhua SUN
;
Zibo MA
Author Information
1. 河南中医药大学第一临床医学院,郑州 450046
- Publication Type:Journal Article
- Keywords:
polycystic ovarian syndrome;
insulin resistance;
hyperandrogenaemia;
mitochondria;
oxidative stress
- From:
Chinese Journal of Comparative Medicine
2024;34(11):126-131
- CountryChina
- Language:Chinese
-
Abstract:
Polycystic ovarian syndrome(PCOS)is a prevalent reproductive endocrine metabolic disorder within obstetrics and gynecology.Two pivotal features of PCOS,insulin resistance(IR)and hyperandrogenemia(HA),are both instrumental in its pathogenesis.There exists a discernible correlation between PCOS and mitochondrial oxidative stress,a relationship heavily influenced by various factors,most notably IR and HA.This article endeavors to elucidate the interplay between IR,HA,and mitochondrial oxidative stress while also exploring the impacts of insulin resistance and hyperandrogenemia on mitochondrial oxidative stress among PCOS patients.
