A single-blind randomized controlled trial of effects of exergaming on cognitive function and negative symptoms in schizophrenia
10.3969/j.issn.1000-6729.2025.07.02
- VernacularTitle:运动游戏疗法治疗精神分裂症认知功能和阴性症状单盲随机对照试验
- Author:
Rui TANG
1
;
Kaiyuan ZHANG
;
Kerun GAO
;
Jianfei SHI
Author Information
1. 浙江中医药大学第四临床医学院,杭州 310053
- Publication Type:Journal Article
- Keywords:
exergaming;
schizophrenia;
cognitive function;
negative symptoms
- From:
Chinese Mental Health Journal
2025;39(7):585-590
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of exergaming on the cognitive functions and negative symp-toms in patients with schizophrenia.Methods:Sixty hospitalized patients meeting ICD-10 diagnostic criteria for schizophrenia were randomly assigned to the exergaming group(n=30)and the conventional treatment group(n=30).The exergaming group received structured exergaming therapy in addition to conventional treatment.Cognitive function was assessed with the MATRICS Consensus Cognitive Battery(MCCB)and Mini-Mental State Examina-tion(MMSE),while positive and negative symptoms were evaluated with the Scale for the Assessment of Positive Symptoms(SAPS)and Scale for the Assessment of Negative Symptoms(SANS).Results:Both groups showed significant improvements in the MCCB scores(Trail Making Test,Symbol Coding,Animal Naming,Maze,and Learning Tests)and MMSE scores post-intervention(time main effect,group main effect,and time × group inter-action,Ps＜0.05).The exergaming group showed significantly greater improvements in most cognitive domains compared to the control group.The SANS scores decreased significantly in both groups,with a greater reduction in the exergaming group(P＜0.05).The SAPS scores also declined,but no significant between-group differences were observed(P＞0.05).Conclusion:Exergaming could effectively improve the cognitive deficits and negative symptoms in patients with schizophrenia.
