Recent advance in mechanism of trichloroethylene exposure in inducing Parkinson's disease incidence
10.3760/cma.j.cn115354-20240904-00539
- VernacularTitle:三氯乙烯暴露在帕金森病发病中的作用机制研究进展
- Author:
Yunpeng XU
1
;
Lei ZHANG
;
Xiuyan WEI
;
Zhiqing SUN
;
Wenjuan WU
;
Chen XIE
;
Jian LIU
Author Information
1. 兰州大学第一临床医学院，兰州 730000
- Publication Type:Journal Article
- Keywords:
Parkinson's disease;
Trichloroethylene;
Environmental pollutant
- From:
Chinese Journal of Neuromedicine
2024;23(12):1285-1289
- CountryChina
- Language:Chinese
-
Abstract:
With the acceleration of global industrialization, impact of environmental risk factors on Parkinson's disease (PD) is gradually increased, resulting in an upward trend in PD incidence. Trichloroethylene (TCE), a widely used organic solvent, has been gradually phased out, yet its persistent environmental contamination continues to pose health risks. In recent years, the relationship between TCE exposure and PD incidence has garnered increased attention. This article reviews the chemical properties of TCE, and relationship between TCE exposure and PD incidence and mechanism of trichloroethylene exposure in inducing PD incidence, in order to provide a new research perspective for management of environmental risk factors for PD.
