Effects of 12 week Tai Chi cardiac rehabilitation programs on inflammatory factors and adhesion mole-cules in patients with coronary artery disease
10.3969/j.issn.1001-1242.2024.12.007
- VernacularTitle:12周太极心脏康复方案对冠心病患者炎症因子及黏附分子的影响
- Author:
Qiuyang WEI
1
;
Fang PENG
;
Yameng LI
Author Information
1. 北京师范大学体育与运动学院,北京市,100875;江苏大学体育部
- Publication Type:Journal Article
- Keywords:
Tai Chi cardiac rehabilitation programme;
conventional exercise rehabilitation program;
coronary ar-tery disease;
pro-inflammatory factors;
anti-inflammatory factors;
adhesion molecule
- From:
Chinese Journal of Rehabilitation Medicine
2024;39(12):1790-1796
- CountryChina
- Language:Chinese
-
Abstract:
0bjective:To observe The effects of 12-week Tai Chi Cardiac Rehabilitation Programme(TCCRP)and conven-tional exercise rehabilitation program(CERP)on inflammatory factors and adhesion molecules in patients with coronary heart disease(CHD).Method:Forty-six patients with CHD were jointly recruited from Anzhen Community Service Center at Bei-jing Chaoyang District and Wanjie Rehabilitation Hospital at Shandong Zibo from Oct.2020 to Nov.2021,and were randomly divided into the TCCRP group(n=23)and the CERP group as the control group(n=23)ac-cording to a 1∶1 ratio.Thirty-four patients completed the whole program,14 patients in the TCCRP group and 20 patients in the CERP group.All program were 60 min per time,3 times a week for a total of 12 weeks,including 4 weeks of in-hospital rehabilitation and 8 weeks of remote on-line home-based rehabilita-tion.Inflammatory factors and adhesion molecules were detected before and after the intervention.Result:After 12 weeks of intervention,C-reactive protein(CRP),interleukin 6(IL-6),vascular cell adhe-sion molecule(VCAM-1),and intercell adhesion molecule(ICAM-1)all decreased significantly(P＜0.01).The anti-inflammatory factor interleukin 10(IL-10)increased significantly in the TCCRP group(P＜0.0l).There was no significant difference between the two groups before the intervention(P＞0.05),and the VCAM-1 in the TCCRP group was significantly lower than the CERP group after the intervention(P＜0.05).Conclusion:In patients with coronary heart disease,the 12-week TCCRP and CERP intervention can effectively reduce the levels of pro-inflammatory factors CRP,IL-6 and adhesion molecules ICAM-1 and VCAM-1.The TC-CRP can effectively improve the level of anti-inflammatory factor IL-10 and reduce the expression of adhesion molecule VCAM-1 compared with CERP,which indicate a more positive effect on regulating the balance between pro-inflammatory and anti-inflammatory factors and improving the anti-inflammatory and anti-adhesion ability.
