Research advances of spaceflight-associated neuro-ocular syndrome
10.3760/cma.j.cn113854-20210218-00036
- VernacularTitle:航天相关神经眼综合征研究进展
- Author:
Yan WANG
1
;
Xuemei LIN
1
;
Songdi WU
1
Author Information
1. 西安市第一医院神经眼科 710002
- Publication Type:Journal Article
- Keywords:
Aerospace medicine;
Refractive errors;
Papilledema;
Intracranial hypertension;
Neuro-ocular syndrome
- From:
Chinese Journal of Aerospace Medicine
2022;33(2):118-122
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To provide ideas and references for the prevention and treatment of spaceflight-associated neuro-ocular syndrome (SANS) by reviewing the clinical manifestations and the potential mechanisms of this syndrome. Literature resource and selection References on the subject of SANS published at home and abroad. Literature quotation Forty published literatures were cited. Literature synthesis SANS was originally known as visual impairment and intracranial pressure syndrome. It was first proposed by National Aeronautics and Space Administration in 2011 and was renamed as SANS in 2017. The clinical manifestations of SANS were described as optic disc edema, globe flattening, optic nerve sheath expansion, retinal folds, decreased vision and cotton wool spots. The potential mechanisms of SANS included intracranial hypertension, fragile flow equilibrium partially and one carbon pathway metabolism alterations. Conclusions:In-depth understanding of the clinical manifestations and mechanisms of SANS and developing appropriate preventive measures can provide protection for longer and farther spaceflight.
