Progress in Diagnosis and Treatment of Chronic Intestinal Pseudo-obstruction
10.12376/j.issn.2097-0501.2025.02.005
- VernacularTitle:慢性假性肠梗阻诊治进展
- Author:
Cheng PENG
1
;
Xiuli ZUO
Author Information
1. 中国医学科学院北京协和医院消化内科,北京 100730
- Publication Type:Journal Article
- Keywords:
chronic intestinal pseudo-obstruction;
gastrointestinal motility;
diagnosis;
treatment
- From:
JOURNAL OF RARE DISEASES
2025;4(2):177-184
- CountryChina
- Language:Chinese
-
Abstract:
Chronic intestinal pseudo-obstruction(CIPO)is a rare intestinal motility disorder character-ized by nonspecific clinical manifestations that mimic mechanical intestinal obstruction but lack corroborative evidence of mechanical obstruction,leading to frequent underdiagnosis and misdiagnosis in clinical practice.Based on etiology,CIPO is classified into primary and secondary subtypes,with diagnosis relying on compre-hensive evaluation integrating clinical presentation,imaging findings,gastrointestinal motility testing,and his-topathological analysis.Owing to its complex pathogenesis and significant interindividual variability,CIPO cur-rently lacks standardized diagnostic criteria and effective therapeutic strategies.Its management typically requires multidisciplinary collaboration,emphasizing patient education alongside integrated interventions including nutritional support,pharmacotherapy,endoscopic procedures,and surgeries when indicated.Recent advancements in gastrointestinal motility assessment and molecular biology techniques have facilitated improve-ments in CIPO diagnosis and treatment.This review summarizes current clinical advances in CIPO management to provide practical references for clinicians.
