The occurrence of renal calculi and its correlated risk factors in flying personnel
10.3760/cma.j.cn113854-20210602-00090
- VernacularTitle:飞行人员肾结石发生的影响因素分析
- Author:
Yawei CHEN
1
;
Zheng XIAO
;
Wenjie CAI
;
Lei ZHOU
;
Jian GAO
;
Yinan ZHANG
;
Dong WANG
Author Information
1. 联勤保障部队第九八三医院肾脏内科，天津 300142
- Publication Type:Journal Article
- Keywords:
Renal calculi;
Risk factors;
Retrospective study;
Flying personnel
- From:
Chinese Journal of Aerospace Medicine
2021;32(4):211-217
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To discuss the related influencing factors of renal calculi in flying personnel and to provide the health guidance for reducing the occurrence.Methods:A retrospective study was used to select the flying personnel who were diagnosed as renal calculi in Air Force Healthcare Center for Special Services, Hangzhou from January 2015 to March 2021 as the observation group, and the healthy flying personnel checked in the same sanatorium during the same period were selected as the control group. The general data and laboratory examination results of the two groups were recorded, and binary Logistic regression analysis was used to explore the influencing factors of the occurrence of renal calculi in flight personnel.Results:A total of 112 cases were included in the observation group and 159 cases in the control group. There was no statistical difference in age, flying hours, drinking history and systolic blood pressure between the two groups ( P>0.05). There was no statistical difference in aspartate aminotransferase, urea nitrogen, creatinine and urine pH between the two groups ( P>0.05). The proportion of smoking in the observation group was 73.21%, significantly higher than 27.04% in the control group ( χ2=56.370, P<0.01). Body mass index, diastolic blood pressure, serum uric acid and low-density lipoprotein cholesterol was (24.58±2.17) kg/m 2, (75.65±7.31) mmHg (1 mmHg=0.133 kPa), (391.02±75.17) mmol/L, (3.13±0.86) mmol/L, respectively. The median of alanine aminotransferase, triglyceride, total cholesterol and fasting plasma glucose was 25.0 U/L, 1.43 mmol/L, 5.18 mmol/L, 5.18 mmol/L, respectively, which were significantly higher than those in the control group, and the differences between the two groups were statistically significant ( P<0.05); the median of high-density lipoprotein cholesterol in the observation group was 1.30 mmol/L, lower than that in the control group (1.43 mmol/L), and the difference was statistically significant ( P<0.05). The cases of flying personnel with fatty liver and BMI>24.0 kg/m 2, increased TC, TG, LDL-C and serum uric acid as well as decreased HDL-C were significantly different between 2 groups ( χ2=10.831-57.651, P<0.01). Further analysis by binary Logistic regression showed that non-smoking history ( OR=0.171, P<0.01), body mass index ( OR=1.179, P=0.05), triglyceride ( OR=2.506, P=0.034), fasting plasma glucose ( OR=2.217, P=0.047), serum uric acid ( OR=1.013, P<0.01) were the independent factors influencing the occurrence of renal calculi in flying personnel. Conclusions:Flying personnel with renal calculi in our military mostly have adverse lifestyles and metabolic disorders, among which high body mass index, elevated triglyceride, and elevated serum uric acid may be the independent risk factors affecting the occurrence of renal calculi. Non-smoking may be an independent protective factor against the occurrence of renal calculi.
