Kleine-Levin syndrome presenting with anorexia: a case report
10.3760/cma.j.cn113661-20250207-00054
- VernacularTitle:以厌食为主要表现的克莱恩-莱文综合征1例
- Author:
Rui ZHAO
1
;
Ping YAO
1
;
Yanchao CHEN
1
;
Zhiqiang ZHANG
1
;
Dongsheng LYU
1
Author Information
1. 内蒙古自治区脑科医院（第三医院）睡眠医学中心，呼和浩特 010000
- Publication Type:Journal Article
- Keywords:
Kleine-Levin syndrome;
Polysomnography;
Anorexia;
Periodic hypersomnia
- From:
Chinese Journal of Psychiatry
2025;58(10):778-781
- CountryChina
- Language:Chinese
-
Abstract:
Kleine-Levin Syndrome(KLS)is a rare neurological disease characterized by recurrent episodes of hypersomnia, hyperphagia, hypersexuality, and cognitive and behavioral abnormalities, with complete functional recovery between episodes. Its pathogenesis remains unclear. We report a 33-year-old female with a 17-year clinical course, characterized mainly by recurrent hypersomnia. During episodes, the patient exhibited prominent anorexia, irritability, derealization, and disorientation, followed by brief periods of excitement after episode resolution. Inter-episode periods were entirely normal. Long-term polysomnography monitoring was conducted for a total of 7 792 minutes. Unlike the typical hyperphagia commonly observed in KLS, this case was marked by prominent anorexia, underscoring the clinical heterogeneity of KLS.This report adds to the limited documentation of rare cases in China.
