Proposal for the Guidelines on Off-label Use of Common Psychiatric Medications in China
10.3760/cma.j.cn113661-20250414-00175
- VernacularTitle:《中国精神科常用药品超说明书用药指南》计划书
- Author:
Yulan XIONG
1
;
Nan LI
;
Yujia QIU
;
Tianmei SI
;
Wei HAO
Author Information
1. 北京大学第六医院 北京大学精神卫生研究所 国家卫生健康委员会精神卫生学重点实验室（北京大学）国家精神心理疾病临床医学研究中心（北京大学第六医院），北京100191
- Publication Type:Journal Article
- Keywords:
Guidebooks;
Psychiatric drugs;
Off-label use;
Proposal
- From:
Chinese Journal of Psychiatry
2025;58(10):736-741
- CountryChina
- Language:Chinese
-
Abstract:
Off-label drug use in psychiatry has long been prevelent, with common clinical practices lacking standardized guidance and associated risks warranting close attention. To address the practical needs of frontline clinicians, the Mental Health Branch of the China National Narcotic Drugs Association, in collaboration with multiple institutions, has launched a project to formulate the Guidelines on Off-label Use of Common Psychiatric Medications in China ("Guideline"). The Guidelines focuses on evaluating evidence and formulating recommendations regarding off-label use scenarios of common psychiatric medications, including indications, dosage, administration, and specific populations. It employs standard methodological frameworks, notably the GRADE-ADOLOPMENT approach (Grading of Recommendations Assessment, Development, and Evaluation Evidence to Decision frameworks for adoption, adaptation, and de?novo development of recommendations), to ensure both scientific rigor and practical applicability. This proposal systematically outlines the background, objectives, processes, organizational structure, and methodologies of the Guideline, aiming to provide psychiatrists with practical and evidence-based prescribing recommendations.
