The current status, problems, and countermeasures of brain imaging research on mental disorders
10.3760/cma.j.cn113661-20250428-00196
- VernacularTitle:精神疾病脑影像学研究现状、问题与对策
- Author:
Lulu ZHANG
1
;
Jingping ZHAO
;
Wenbin GUO
Author Information
1. 广州市第一人民医院精神心理科，广州510180
- Publication Type:Journal Article
- Keywords:
Mental illness;
Magnetic resonance imaging;
Brain imaging;
Heterogeneity
- From:
Chinese Journal of Psychiatry
2025;58(12):877-882
- CountryChina
- Language:Chinese
-
Abstract:
There are heterogeneity and complexity of symptoms across disease lineages in psychiatric disorders, and there lack objective biological markers. With the development of neuroimaging research, breakthroughs in neuroimaging techniques such as high-resolution magnetic resonance imaging, resting state functional connectivity analysis, and molecular imaging have provided new methods for exploring the neuropathological mechanisms of psychiatric disorders. Although rapid progress has been made in the study of brain imaging in psychiatric disorders, challenges still exist such as sample heterogeneity, limitations in diagnostic criteria, and research reproducibility. In the future, efforts can be made to build a "bridge" between brain imaging research and diagnosis through large-scale collaboration, establishing standardized processes, interpretable AI models, and optimizing deep learning models.
