A case of dementia with Lewy bodies with rapid eye movement sleep behavior disorder as the initial symptom
10.3760/cma.j.cn113661-20240519-00151
- VernacularTitle:以快速眼动睡眠行为障碍为首次发病症状的路易体痴呆1例
- Author:
Ruonan DU
1
;
Xin WANG
;
Jianxin ZHANG
;
Jianyi ZHANG
;
Zhiren WANG
;
Xiaole HAN
;
Haipeng CAI
Author Information
1. 北京大学回龙观临床医学院，北京 100096
- Publication Type:Journal Article
- Keywords:
Dementia;
Lewy body disease;
Cognitive impairment;
Visual hallucination;
Rapid eye movement sleep behaviour disorder
- From:
Chinese Journal of Psychiatry
2025;58(4):288-291
- CountryChina
- Language:Chinese
-
Abstract:
A 77-year-old male patient was admitted to the hospital with the main cause of memory loss, visual hallucination for more than one year, aggravated for two months with sensitivity and paranoia. The patient exhibited signs of loss of smell, axial hypertonia, upper limb hypertonia, slow start, and propulsive gait. Cranial MRI suggested cerebral atrophy, bilateral hippocampal atrophy, and multiple cavernous cerebral infarcts. Severe memory deficits, moderate intellectual deficits, MMSE score of 12, mildly abnormal electroencephalography, and polysomnographic monitoring suggested a high likelihood of apnea syndrome. Prior to the onset of the disease, the patient had a history of swinging, shouting, and cursing during nighttime sleep, according to his family members. The final diagnosis was Lewy body dementia.
