Clinical efficacy of Jiawei Tai Yuan Yin combined with allylestradiol tablets in the treatment of early threatened abortion complicated with subchorionic hematoma
- VernacularTitle:胎元饮加味联合烯丙雌醇片治疗早期先兆流产合并绒毛膜下血肿的临床疗效
- Author:
Xiaolei YANG
1
;
Wen FENG
;
Xuelian XU
Author Information
- Publication Type:Journal Article
- Keywords: abortion,threatened; chorion; hematoma; Tai Yuan Yin; allylestrenol; CA-125 antigen; cuscutae semen
- From: Tianjin Medical Journal 2025;53(8):870-874
- CountryChina
- Language:Chinese
- Abstract: Objective To investigate the clinical efficacy of Jiawei Tai Yuan Yin combined with allylestradiol tablets for the treatment of early threatened abortion complicated by subchorionic hematoma(SCH).Methods A total of 120 patients with early threatened miscarriage combined with SCH were selected and divided into the observation group(Jiawei Tai Yuan Yin+allylestradiol tablets,60 cases)and the control group(allylestradiol tablets,60 cases)according to the treatment regimen.Seven days was one course of treatment,and both groups of patients were treated for two courses.Changes of traditional Chinese medicine(TCM)syndrome score before treatment and 14 days after treatment,clinical efficacy,SCH area,the ratio of SCH area to gestational sac area,vaginal bleeding(duration and volume),the miscarriage rate in the early stage of pregnancy,the ratio of auxiliary T cells to inhibitory T cells(Th/Ts)and the level of carbohydrate antigen 125(CA125)were observed.Results After 14 days of treatment,TCM syndrome scores,SCH area,the ratio of SCH area to gestational sac area,the Th/Ts ratio and the CA125 level were decreased in the two groups,and those of the observation group were lower than those of the control group(P＜0.05).After 14 days of treatment,the total effective rate was higher in the observation group than that of the control group(P＜0.05).During the treatment period,the duration of vaginal bleeding,the amount of vaginal bleeding and the miscarriage rate in the early stage of pregnancy were lower in the observation group than those in the control group(P＜0.05).Conclusion The combination of Jiawei Tai Yuan Yin and allylestradiol tablets can effectively treat early threatened miscarriage with SCH,thereby reducing the miscarriage rate in early pregnancy.
