Efficacy and influencing factors of cognitive behavior therapy combined with SSRIs in the treatment of major depressive disorder
10.3760/cma.j.cn113661-20240527-00161
- VernacularTitle:认知行为疗法联合选择性5-羟色胺再摄取抑制剂治疗抑郁症的疗效及影响因素研究现状与展望
- Author:
Shujun HOU
1
;
Jinyang LI
;
Chun WANG
Author Information
1. 南京师范大学心理学院，南京 210024
- Publication Type:Journal Article
- Keywords:
Depressive disorder;
Cognitive therapy;
Selective serotonin reuptake inhibitors;
Combination therapy
- From:
Chinese Journal of Psychiatry
2025;58(5):384-391
- CountryChina
- Language:Chinese
-
Abstract:
To date, most studies support the combination therapy of cognitive behavioral therapy (CBT) and selective serotonin reuptake inhibitors (SSRIs) compared to monotherapy in adolescents, adults, and older adults with major depressive disorder. However, the results were inconsistent. This article reviews the efficacy and influencing factors of CBT combined with SSRIs in the treatment of adolescents, adults, and elderly patients with major depressive disorder. It is suggested that the efficacy of this combination therapy is related to the severity of depression, cognitive function, education level, responsiveness to treatment, duration of treatment and end time of treatment, and the shortcomings and prospects of the previous research are put forward.
