The relationship between PM 2.5 exposure concentration in different environments during pregnancy and iodine nutritional level of pregnant women
10.3760/cma.j.cn231583-20240604-00162
- VernacularTitle:孕期不同环境PM 2.5暴露浓度与孕妇碘营养水平关系研究
- Author:
Jing ZHOU
1
;
Chang WANG
;
Ruonan FU
;
Abuduwaili DANNIER
;
Tayier RISHALAITI
;
Ling ZHANG
;
Chenchen WANG
Author Information
1. 新疆医科大学公共卫生学院，乌鲁木齐 830054
- Publication Type:Journal Article
- Keywords:
Pregnant women;
Early pregnancy;
Fine particulate matter;
Iodine nutrition level;
Maternal and infant health
- From:
Chinese Journal of Endemiology
2024;43(12):947-953
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate whether there is an correlation between exposure to fine particulate matter (PM 2.5) in different environments during pregnancy and iodine nutritional levels of pregnant women. Methods:From March to August 2023, a case-control study method was used to select Midong District of Urumqi City with severe PM 2.5 pollution and Bole City of Bortala Mongolian Autonomous Prefecture with higher air quality index as the survey sites. Pregnant women before 28 weeks of pregnancy who voluntarily participated in this study and met the inclusion and exclusion criteria, were selected as the study subjects at the above locations. The basic information of the study subjects was investigated in the form of questionnaires. Whole blood, saliva, and urine samples were collected from the study subjects to determine serum iodine, salivary iodine, urinary iodine, and urinary creatinine levels. The average daily PM 2.5 exposure concentrations of pregnant women in outdoor, indoor, and multiple environments were calculated in Midong District and Bole City, respectively. The correlation between PM 2.5 exposure concentrations in different environments during pregnancy and iodine nutrition level of pregnant women was analyzed through a generalized linear model. Results:Midong District included 157 pregnant women, and Bole City included 145 pregnant women. There were statistically significant differences in the outdoor daily average PM 2.5 exposure concentration, indoor daily average PM 2.5 exposure concentration, daily maximum PM 2.5 exposure concentration in multiple environments, and daily minimum PM 2.5 exposure concentration in multiple environments among pregnant women between the two regions ( P < 0.05). The serum iodine [ M ( Q1, Q3): 83.99 (71.93, 93.39), 86.93 (76.90, 98.31) μg/L] and salivary iodine levels [76.90 (44.93, 140.36), 50.22 (24.12, 82.77) μg/L] of pregnant women in the two regions were compared, and the differences were statistically significant ( P < 0.05). The overall indoor and outdoor daily average PM 2.5 exposure concentrations of pregnant women in Midong District and Bole City were positively correlated with salivary iodine levels ( P < 0.001), and the daily minimum PM 2.5 exposure concentration in multiple environments was positively correlated with serum iodine levels ( P = 0.019). Conclusion:There are differences in iodine nutrition levels among pregnant women in different PM 2.5 exposure areas, and exposure to PM 2.5 during pregnancy may lead to fluctuations in iodine nutrition levels among pregnant women.
