Evaluation of bone salt metabolism levels in 40 patients with acute brucellosis complicated by decreased serum calcium levels
10.3760/cma.j.cn231583-20231121-00114
- VernacularTitle:评估40例急性布鲁氏菌病合并血清钙水平降低患者骨盐代谢水平
- Author:
Yi HOU
1
;
Lihong HAN
;
Shuyi MA
Author Information
1. 包头市中心医院体检科，包头 014040
- Publication Type:Journal Article
- Keywords:
Brucellosis;
Parathyroid hormone;
25-hydroxyvitamin D 3;
Calcium
- From:
Chinese Journal of Endemiology
2024;43(12):1001-1003
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the bone salt metabolism levels of patients with acute brucellosis complicated by decreased serum calcium levels.Methods:Forty patients with acute brucellosis complicated by decreased serum calcium levels diagnosed by the Disease Prevention and Control Center of Donghe District, Baotou City from January to December 2021 were selected as the low calcium acute brucellosis group, and 30 local healthy people were selected as the control group. The fully automatic chemiluminescence immunoassay analyzer was used to determine the levels of regulatory hormone indicators such as serum parathyroid hormone (PTH), 25-hydroxyvitamin D 3 [25-(OH)VD 3], and bone mineral indicators such as serum calcium, phosphorus, and magnesium. The expression difference of the above indexes between the two groups was compared. Results:Compared with the control group, the serum PTH and 25-(OH)VD 3 levels in the low calcium acute brucellosis group were lower [(23.15 ± 9.78) vs (54.34 ± 15.31) pg/ml, (16.68 ± 5.48) vs (46.23 ± 16.79) ng/L, t = 4.96, 15.03, P < 0.001]; the serum calcium level was lower [(0.94 ± 0.14) vs (1.23 ± 0.23) mmol/L, t = 6.11, P < 0.001], while the serum phosphorus and magnesium levels were higher [(2.98 ± 0.68) vs (1.90 ± 0.25) mmol/L, (1.13 ± 0.21) vs (0.90 ± 0.48) mmol/L, t = 7.51, 7.70, P < 0.001]. Conclusion:Patients with acute brucellosis complicated by decreased serum calcium levels may experience abnormal bone salt metabolism hormones.
