A case of early-onset Kleine-Levin syndrome in adolescence
10.3760/cma.j.cn113661-20240425-00133
- VernacularTitle:青少年早发克莱恩-莱文综合征1例
- Author:
Yuejiao MA
1
;
Jianchang XU
1
;
Xiujuan LI
1
;
Yingyuan LI
1
;
Yi LI
1
;
Qiuyan LIN
1
;
Jianping LU
1
Author Information
1. 深圳市精神卫生中心 深圳市康宁医院儿少精神科,深圳 518020
- Publication Type:Journal Article
- Keywords:
Kleine-Levin syndrome;
Adolescent;
Recurrent-remitting sleep disorder
- From:
Chinese Journal of Psychiatry
2025;58(1):55-58
- CountryChina
- Language:Chinese
-
Abstract:
Kleine-Levin syndrome (KLS) is a rare, recurrent-remitting sleep disorder characterized by periodic hypersomnia, hyperphagia, and hypersexuality, accompanied by cognitive dysfunction, perceptual disturbances, mood changes, or psychiatric abnormalities. Patients typically experience recurrent episodes, with hypersomnic periods lasting from several days to weeks. Most KLS patients exhibit normal functions during the intermission period, while early-onset KLS cases in adolescents are rare, often presenting with frequent episodes and complex symptoms, which can easily lead to misdiagnosis. Therefore, this case report analyzed the detailed medical history, laboratory findings, differential diagnosis, and treatment of a teenage patient with KLS, along with a review of the literature. This case aims to provide a deeper understanding of the complex symptoms and diagnostic challenges associated with early-onset KLS in adolescents.