New Research progress in virulence factors of Streptococcus suis
10.3969/j.issn.1002-2694.2025.00.071
- VernacularTitle:猪链球菌毒力因子研究新进展
- Author:
Yu-jie WEI
1
;
Da-han YANG
1
;
Xue-wu YU
1
Author Information
1. 内蒙古民族大学动物科技学院,通辽 028000
- Publication Type:Journal Article
- Keywords:
Streptococcus suis;
virulence factor;
innate immune
- From:
Chinese Journal of Zoonoses
2025;41(6):648-652
- CountryChina
- Language:Chinese
-
Abstract:
Streptococcus suis is an important zoonotic pathogen.Two outbreaks of large-scale human infections with S.suis have occurred in China,thereby posing a serious public health risk and changing the view that this pathogen causes only sporadic cases in humans.Deeper understanding of the pathogenesis of Streptococcus suis is urgently needed.During the infection process,S.suis sur-vival and virulence in the host is facilitated by circumvention of the immune defense through various virulence factors.The bacterium's pathogenicity is closely associated with the virulence factors it carries.Herein,we review recent progress in the study of virulence fac-tors of S.suis related to overcoming the host intrinsic immune defense,to provide a theoretical basis for the prevention of porcine strep-tococcal diseases and the development of vaccines.