Research progress on the treatment of depression with transcranial alternating current stimulation at different frequencies
10.3760/cma.j.cn113661-20231116-00214
- VernacularTitle:不同频率经颅交流电刺激对抑郁症治疗的研究进展
- Author:
Xuelin ZHANG
1
;
Lan ZHANG
1
;
Xiaying SI
1
;
Ke WANG
1
;
Peishan HUANG
1
;
Yi MIAO
1
;
Qiangli DONG
1
Author Information
1. 兰州大学第二医院心理卫生科，兰州 730000
- Publication Type:Journal Article
- Keywords:
Depressive disorder;
Transcranial alternating current stimulation;
Neural oscillation;
Frequency;
Therapy
- From:
Chinese Journal of Psychiatry
2024;57(11):778-782
- CountryChina
- Language:Chinese
-
Abstract:
Depression is a common mental disorder characterized primarily by low mood accompanied by cognitive and behavioral changes. The commonly used antidepressants are not fast onset. Even with a long term pharmacotherapy, relapse rate is still quite high. Transcranial alternating current stimulation (tACS) is a non-invasive brain stimulation technique that has been increasingly used in the treatment of depression in recent years. Since depression is associated with abnormalities in endogenous neural oscillations and synaptic plasticity in the brain, tACS can influence these process, thereby treating depression. Different frequencies of tACS stimulation can improve depressive symptoms, with gamma (γ) and alpha (α) frequencies receiving the most attention. This article primarily reviews the potential mechanisms of tACS and the application of tACS at different frequencies in treating depression, aiming to further explore the feasibility of tACS in the treatment of depression.
