Isolation,identification,and biological characterization of a Streptococcus equinus strain from sheep
10.3969/j.issn.1002-2694.2025.00.098
- VernacularTitle:一株羊源马肠链球菌的分离鉴定及生物学特性分析
- Author:
Hai-li WANG
1
;
Xiu-sheng YIN
;
Qi JIA
;
Feng-yuan ZHANG
;
Ling MO
;
Lin LI
;
Jing DONG
;
Jin-liang WANG
Author Information
1. 聊城职业技术学院,聊城 252000
- Publication Type:Journal Article
- Keywords:
sheep;
Streptococcus equinus;
isolation and identification;
drug susceptibility testing;
genome analysis
- From:
Chinese Journal of Zoonoses
2025;41(6):641-647
- CountryChina
- Language:Chinese
-
Abstract:
Streptococcus equinus is a zoonotic disease that can cause illness in various animals under specific environmental condi-tions.No reports have described isolation of this bacterium from the liver in affected sheep.This study successfully isolated and identi-fied a strain of Streptococcus equinus through bacterial isolation and culture,Gram staining,drug sensitivity testing,mouse sensitivity testing,bacterial biochemical testing,and whole genome sequencing.The strain was found to have pathogenicity toward Kunming white mice,and to be sensitive to four antibiotics(penicillin,ampicillin,ceftiofur sodium,and ceftriaxone sodium)but resistant to four antibiotics(streptomycin,amoxicillin,tetracycline,and gentamicin).On the basis of drug sensitivity testing,targeted treatment of the affected sheep flock with ceftiofur sodium effectively controlled the disease within 2 days,and no new cases occurred.This study provides a reference for biological characterization of ovine Streptococcus equinus;public health;and the investigation of disease pre-vention,control,and epidemiology.
