The role of nectins in stress-induced brain functional and structural damage
10.3760/cma.j.cn113661-20231109-00200
- VernacularTitle:Nectins在应激所致大脑功能与结构损伤中的作用
- Author:
Hongli WANG
1
;
Jitao LI
;
Yingying ZHAO
;
Tianmei SI
Author Information
1. 首都医科大学附属北京安定医院 国家精神心理疾病临床医学研究中心 精神疾病诊断与治疗北京市重点实验室 抑郁障碍病理机制联合实验室(首都医科大学),北京 100088
- Publication Type:Journal Article
- Keywords:
Central nervous system;
Stress;
Nectins
- From:
Chinese Journal of Psychiatry
2024;57(10):704-708
- CountryChina
- Language:Chinese
-
Abstract:
Stress damages the function and structure of the brain and then becomes one of the risk factors for many psychiatric disorders. Nectins were recently discovered as cell adhesion molecules mediating many types of intercellular connections, especially synaptic connections between neurons, and thus involved in various physiological and pathological processes. Based on preclinical studies, the paper reviews the role of nectins in stress-induced functional and structural disorders of the central nervous system and the possible mechanisms involved.