Peripheral neuropathy induced by lamivudine
10.3760/cma.j.issn.1008-5734.2015.01.011
- VernacularTitle:拉米夫定致周围神经病
- Author:
Xiaowei ZHAO
1
;
Hongli CHEN
1
;
Canli XU
1
Author Information
1. 100015,首都医科大学附属北京地坛医院门诊
- Publication Type:Journal Article
- Keywords:
Lamivudine;
Peripheral nervous system diseases
- From:
Adverse Drug Reactions Journal
2015;17(1):54-54
- CountryChina
- Language:Chinese
-
Abstract:
A 56-year-old female patient with chronic hepatitis B was treated with lamivudine 100 mg once daily.Three years later,the patient developed numbness of extremities.Electromyography showed slower sensory nerve conduction velocity.She was given treatment with vitamin B1 and mecobalamin for two months,but her symptoms was not improved.Lamivudine was discontinued and therefore switched to adefovir dipivoxil 100 mg once daily.Two months later,her symptom of numbness improved significantly.
