Analysis of the clinical efficacy of autologous platelet-poor plasma combined with concentrate growth factors in the treatment of young traumatic permanent teeth
10.3969/j.issn.1001-3733.2025.04.008
- VernacularTitle:自体贫血小板血浆联合浓缩生长因子在年轻恒牙牙外伤治疗中的临床疗效分析
- Author:
Jiaoru HUO
1
;
Yueyue ZHONG
;
Rui TUO
Author Information
1. 716000,延安大学附属医院口腔医院牙体牙髓病科
- Publication Type:Journal Article
- Keywords:
Young permanent teeth;
Dental trauma;
Chronic apical periodontitis;
Autologous platelet-poor plasma;
Concen-trate growth factors
- From:
Journal of Practical Stomatology
2025;41(4):484-489
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the efficacy in the treatment of chronic apical periodontitis caused by dental trauma in young permanent teeth with the combination of autologous platelet-poor plasma(PPP)and concentrate growth factors(CGF).Methods:80 young children with chronic apical periodontitis of permanent teeth admitted to the Department of Dentistry and Endodontics of Stomatological Hospital from September 2021 to September 2023 were included,and the patients were divided into three groups A,B and C using a computer-generated random number table.Group A was treated with bioceramic material iRoot BP Plus.Group B was treated with CGF,and Group C was treated with CGF combined with PPP.Clinical and imaging evaluations were performed af-ter treatment.Results:At the last follow-up,the treatment effectiveness rate of the CGF+PPP group was 85.71％,which was sig-nificantly higher than the 52.00％of the iRoot BP Plus group and 59.26％of the CGF group(P＜0.05).In terms of root develop-ment,the root canal length and root canal wall thickness increased more significantly in the CGF+PPP group after treatment(P＜0.05).Regarding the reduction in periapical lesion volume,the reduction in lesion volume in the CGF+PPP group was more obvi-ous(P＜0.05).Comparing the recovery status of the affected teeth after treatment,the proportion of normal pulp vitality and normal tooth color in the CGF+PPP group was significantly higher than that in the iRoot BP Plus group(P＜0.05).Conclusion:Autolo-gous platelet-poor plasma combined with CGF can more effectively promote tooth root development and lesion healing than iRoot BP Plus or CGF alone in the treatment of chronic apical periodontitis caused by trauma to young permanent teeth.
