Ioversol injection induced cortical blindness
10.3760/cma.j.issn.1008-5734.2015.05.022
- VernacularTitle:碘佛醇注射液致皮质盲
- Author:
Yongzhen WANG
1
;
Yanhua WANG
;
Shijie NA
;
Feng DAI
;
Guojin HUANG
;
Di HU
Author Information
1. 210003,东南大学附属第二医院/南京市第二医院介入血管科
- Publication Type:Journal Article
- Keywords:
Contrast media;
Blindness,cortical;
Brain infarction
- From:
Adverse Drug Reactions Journal
2015;17(5):389-390
- CountryChina
- Language:Chinese
-
Abstract:
A 54-year-old male patient with chronic hepatitis B and liver cirrhosis with upper gastrointestinal hemorrhage was treated with the percutaneous transhepatic embolization of gastroesophageal varices and partial splenic embolization.He received an intravenous ioversol injection 160 ml.About 6.5 hours after intervention, the patient became blind in both eyes.Magnetic resonance imaging (MRI) showed widely fresh brain infarction, but nothing abnormal was found in brain computed tomography.He was given oxygen and dexamethasone, sodium aescinate, mannitol, alprostadil, vinpocetine, ligustrazine,monosialotetrahexosyl ganglioside sodium.Fifty-eight hours after blindness, the eyesight was completely resumed.Two weeks later, MRI showed that the range of cerebral infarcts became smaller, signal intensity was reduced.Fourteen months later, the gastrointestinal hemorrhage did not occur and the eyesight was normal.
