Hemafecia due to icotinib hydrochloride
10.3760/cma.j.issn.1008-5734.2016.04.015
- VernacularTitle:盐酸埃克替尼致便血
- Author:
Xiuli LIN
1
;
Huiqing ZENG
1
;
Xueying CAI
1
Author Information
1. 361004,厦门大学附属中山医院/福建医科大学厦门中山教学医院呼吸内科
- Publication Type:Journal Article
- Keywords:
Icotinib;
Hemafecia
- From:
Adverse Drug Reactions Journal
2016;18(4):300-301
- CountryChina
- Language:Chinese
-
Abstract:
A 68-year-old female patient received icotinib hydrochloride 0.125 mg thrice daily due to lung cancer with systemic multiple bone metastases.On the second day,the patient developed hematochezia with an amount of 20 ml blood in stool.Icotinib hydrochloride was stopped by herself.On the third day,hemafecia disappeared.On the fourth day,she restarted icotinib hydrochloride at the same dosage following the doctor's advice.On the 5th day,hemafecia three times appeared,which was about 100-150 ml.Laboratory tests showed that platelet was 43 × 109/L (37 × 109/L before the drug administration) and hemoglobin was 119 g/L(132 g/L before the drug administration).Icotinib hydrochloride was withdrawn and the hemafecia did not recur for 4 days.
