Application progress of histological scores in disease activity assessment of inflam-matory bowel disease
10.13315/j.cnki.cjcep.2025.07.014
- VernacularTitle:组织学评分在炎症性肠病疾病活动性评估中的应用与进展
- Author:
Yangyang FENG
1
;
Hualiang XIAO
1
Author Information
1. 陆军军医大学大坪医院病理科,重庆 400042
- Publication Type:Journal Article
- Keywords:
ulcerative colitis;
Crohn's disease;
histology;
score;
histological remission;
literature review
- From:
Chinese Journal of Clinical and Experimental Pathology
2025;41(7):929-934
- CountryChina
- Language:Chinese
-
Abstract:
The histological assessment has been considered as a detailed and accurate method for measuring the disease activity in inflammatory bowel disease(IBD).In ulcerative colitis(UC),histological activity has been demon-strated to be associated with a higher rate of relapse,prolonged corticosteroid use and long-term complications,even in patients who have achieved endoscopic remission.Therefore,histological remission may be regarded as a potential ther-apeutic target.This article introduces the clinical significance of disease activity assessment in IBD,focusing on the re-view of validated and newly proposed histological scoring systems for IBD,and explores the priorities for future research needs.
